Diversification and its Determinants: A Search for Alternative Income and Agricultural Development in Eastern India

The eastern region of India, comprising the states of Bihar, Jharkhand, Assam, Odisha and West Bengal, is one of the most backward regions of the nation. This region occupies about 21.85% of geographical area and supports 34% of the population of the country. Agriculture is the mainstay of economy in the region. About 67% of the cultivators belong to marginal group and over 75% of their earnings are utilized to ensure their food security. Issues related to diversification have been discussed by researchers for a long period and they have been trying to relate diversification to the developmental prospects and various factors responsible for it. Despite this, the eastern region has rich natural resources i.e. fertile land, abundant ground water (145.12 BCM), however, the pace of agricultural development is very slow. In the present study, an attempt has been made to measure diversification using Herfindahl-Hirschman index, known as the most popular method, it was used to measure extent of diversification. The regression model was applied to access the determinants of crop diversification in the region. The study is based on secondary data collected from various published sources from 2001-02 to 2014-15 i.e. for a period of 14 years. The results revealed that in the region, the diversification for the study period was observed very low in almost all the states under study and for the eastern region as a whole. The study pinpointed the fact that despite the rich natural resources, its potential could not be harnessed from the point of view of improving agricultural productivity, poverty alleviation and livelihood improvement. Strengthening of crop diversification depends on market and taking care of production risks through technological support, quality input supply, more insurance coverage and establishment of modern storage-processing centres in the region. Keeping in view the rich natural resources and hidden agricultural development opportunities in the region, government has already taken initiative for Second Green Revolution from the region, however a strong policy push up towards instilling confidence among the farming community is needed in this direction

Diversification and its Determinants: A Search for Alternative Income and Agricultural Development in Eastern India

The eastern region of India, comprising the states of Bihar, Jharkhand, Assam, Odisha and West Bengal, is one of the most backward regions of the nation. This region occupies about 21.85% of geographical area and supports 34% of the population of the country. Agriculture is the mainstay of economy in the region. About 67% of the cultivators belong to marginal group and over 75% of their earnings are utilized to ensure their food security. Issues related to diversification have been discussed by researchers for a long period and they have been trying to relate diversification to the developmental prospects and various factors responsible for it. Despite this, the eastern region has rich natural resources i.e. fertile land, abundant ground water (145.12 BCM), however, the pace of agricultural development is very slow. In the present study, an attempt has been made to measure diversification using Herfindahl-Hirschman index, known as the most popular method, it was used to measure extent of diversification. The regression model was applied to access the determinants of crop diversification in the region. The study is based on secondary data collected from various published sources from 2001-02 to 2014-15 i.e. for a period of 14 years. The results revealed that in the region, the diversification for the study period was observed very low in almost all the states under study and for the eastern region as a whole. The study pinpointed the fact that despite the rich natural resources, its potential could not be harnessed from the point of view of improving agricultural productivity, poverty alleviation and livelihood improvement. Strengthening of crop diversification depends on market and taking care of production risks through technological support, quality input supply, more insurance coverage and establishment of modern storage-processing centres in the region. Keeping in view the rich natural resources and hidden agricultural development opportunities in the region, government has already taken initiative for Second Green Revolution from the region, however a strong policy push up towards instilling confidence among the farming community is needed in this direction

Synthesis and antibacterial evaluation of 2-(1,3- Benzodioxol-5-ylcarbonyl)arylsulfonohydrazide derivatives

Purpose: To study the antibacterial activity of various sulfonamides derived from 1,3-benzodioxol-5- carbohydrazide.Methods: The synthesis involved the conversion of 1,3-benzodioxol-5-carboxylic acid (1) to ethyl 1,3- benzodioxol-5-carboxylate (2) and then to 1,3-benzodioxol-5-carbohydrazide (3). The target molecules, 2-(1,3-benzodioxol-5-ylcarbonyl)arylsulfonohydrazide derivatives (5a-l) were synthesized through a benignant method from aqueous medium by the reaction of 3 and arylsulfonyl chlorides (4a-l). The structural formulae of the synthesized compounds were characterized by infra red spectroscopy (IR), proton nuclear magnetic resonance (1H-NMR) and electron impact mass spectrometry (EI-MS). The compounds were screened for in vitro antibacterial activity by determining their minimum inhibitory concentration (MIC).Results: The molecule, 5k, bearing 2-hydroxy-3,5-dichlorophenyl group exhibited the highest activity with MIC of 11.92 ± 3.40 (S. typhi), 8.37 ± 2.22 (E. coli), 9.28 ± 2.31 (P. aeroginosa), 11.76 ± 1.30 (B. subtilis) and 10.30 ± 1.63 (S. aureus) μmoles/L relative to that of ciprofloxacin with 9.42 ± 1.09, 8.02 ± 2.17, 8.11 ± 1.32, 8.88 ± 2.00 and 9.23 ± 1.87 μmoles/L respectively.Conclusion: The most potent of the synthesized compounds (5k) posesses moderate activity against all the bacterial strains, while 5g remained completely inactive.Keywords: 1,3-Benzodioxol-5-carboxylic acid, Antibacterial activity, Sulfonohydrazide, Synthesi

Diversity of Bacteria and Fungi Associated with Freshwater Fishes from Mijawal River, Nasarawa, Nigeria

Understudying the presence of bacteria and fungi population on freshwater fishes, provides the knowledge and understanding of their diversity and potential roles they may play in the health of the aquatic and terrestrial ecosystems. The present study was conducted to evaluate the diversity of bacteria and fungi species of identified fish samples from River Mijawal, Nasarawa State. The fishes were sampled from the only landing for three months (October to December, 2019) for this study. During the sampling periods, thirteen (13) different fish species were identified; they were swabbed with sterilized swab stick from the skin surface for bacteria and fungi identification. The Dominant fish species were Tilapia zillii , Labeo senegalensis , Mormyrus rume and Mormyrus tapines. The total number of thirteen (13) bacterial and five (5) fungi species were isolated and identified. Eight (8) of the bacteria isolates, were gram negative bacteria ( Pseudomonas sp, Aeromonas sp, Serratia mercescenes , Proteus sp, Salmonella spp, Escherichia coli , Klebsiella sp, and Enterobacter sp.); whilst the other five (5) were gram positive bacteria ( Bacillus sp, Micrococcus sp, Staphylococcus sp, Enterococcus sp and Listeria monocytogenes ).The five isolated fungi species were Aspergillus niger , Rhizopus sp, Penicillium sp, Trichoderma viridae and Geotrichum candidum . The frequency of occurrence of the isolated bacteria indicated that Staphylococcus sp had the highest frequency of occurrence (16.67%) while Serratia mercescens had the least occurrence (2.78%). The highest number of occurrence of the isolated fungi species was observed in Rhizopus sp while the least was recorded in Geotricum candidum. It was observed that Tilapia zillii and Mormyrus rume had the most frequent bacteria and fungi isolates. It can therefore be deduced from the results that fish samples identified from River Mijawal has high bacteria and fungi diversity that may be pathogenic to man. The occurrence of these microbes may be attributed of human and animal faeces in the Rive

Synthesis and Evaluation of some New 5-Substituted-1,3,4- oxadiazol-2yl-4-(morpholin-4yl Sulfonyl)benzyl Sulfides as Antibacterial Agent

Purpose: To synthesise a new series of 5-substituted-1,3,4-Oxadiazol-2yl-4-(morpholin-4yl sulfonyl)benzyl sulfide and evaluate their antibacterial activity.Methods: Different organic acids were converted consecutively into corresponding esters, hydrazides and 5-substituted-1,3,4-Oxadiazol-2-thiols (4a-e). The targets, 6a-e were synthesized by stirring 4a-e with 4-(4-(bromomethyl)phenylsulfonyl) morpholine (5) in the presence of N,N-dimethylformamide (DMF) and sodium hydride (NaH). All the structures were elucidated by modern spectroscopic techniques and screened against bacteria using standard procedure and ciprofloxacin drug as positive control.Results: The yield of the synthesized compounds (4a-e and 6a-e) were moderate (65 - 90 %). Compounds 6a-e had antibacterial activity against Pseudomonas aeruginosa, Bacillis subtilis and Staphylococcus aureus while some had activity against the other bacteria used. One of the compounds, 6b, exhibited significant activity against all the bacterial strains, i.e., S. typhi (-), E. coli (-), K. pneumoniae (-), P. aeruginosa (-), B. subtilis (+) and S. aureus (+) with  MIC (μM) values of 11.01 ± 0.31, 15.37 ± 3.33, 16.11 ± 1.14, 9.70 ± 1.96, 10.01 ± 2.70 and 9.15 ± 0.29, respectively. However, none of the compounds had any inhibitory activity against any bacteria as high as that of ciprofloxacin.Conclusion: Five new compounds with antibacterial activities have been synthesized. Their potential as therapeutic agents is, however, yet to be evaluated.Keywords: 1,3,4-Oxadiazole, Benzyl sulfide, 4-(4-(bromomethyl)phenylsulfonyl)morpholine, Spectral analysis, Antibacterial activit

Popliteal lymph node dissection for metastatic squamous cell carcinoma: a case report of an uncommon procedure for an uncommon presentation

Lymph node metastasis from cutaneous squamous cell carcinoma is uncommon. The popliteal fossa is rarely involved with metastasis. Popliteal lymph node dissection is uncommonly performed and not frequently discussed in the literature. We present a case of squamous cell carcinoma of the heel with popliteal and inguinal metastasis. This is followed by a description of the relevant anatomy of the popliteal fossa and the technique of popliteal lymphadenectomy

The Sandwell Project: A controlled evaluation of a programme of targeted screening for prevention of cardiovascular disease in primary care

<p>Abstract</p> <p>Background</p> <p>A pilot cardiovascular disease prevention project was implemented in the inner-city West Midlands. It was evaluated by comparing its effectiveness to a control group where full implementation was delayed by a year.</p> <p>Methods</p> <p>Cardiovascular risk factor data were extracted on all untreated patients 35 to 74 years old from electronic medical databases in six general practices. A best estimate of ten-year CVD risk cardiovascular risk was calculated on all patients using the extracted risk factor data. Default risk-factor values were used for all missing risk factor data. High risk patients were thus identified. In four practices a project nurse systematically invited, assessed and referred high risk patients for treatment. Two control practices were provided with a list of their high risk patients. The outcomes were the proportions of untreated high-risk patients who were assessed, identified as eligible for treatment and treated under two strategies for identifying and treating such patients in primary care.</p> <p>Results</p> <p>Of all high-risk patients suitable for inclusion in the project, 40.6% (95% CI: 36.7 to 45.7%) of patients in intervention practices were started on treatment were started on at least one treatment, compared to 12.7% (95% CI: 9.8% to 16.1%) in control practices.</p> <p>Conclusion</p> <p>A strategy using electronic primary care records to identify high risk patients for CVD prevention works best with a process for acting on information, ensuring patients are invited, assessed and treated.</p